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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNQ3 All Species: 22.73
Human Site: T246 Identified Species: 62.5
UniProt: O43525 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43525 NP_004510.1 872 96742 T246 R M D R R G G T W K L L G S A
Chimpanzee Pan troglodytes XP_001134760 872 96660 T246 R M D R R G G T W K L L G S A
Rhesus Macaque Macaca mulatta XP_001089122 951 105836 T325 R M D R R G G T W K L L G S A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8K3F6 873 96778 T247 R M D R R G G T W K L L G S A
Rat Rattus norvegicus O88944 873 96879 T247 R M D R R G G T W K L L G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508650 831 93729 T196 R M D R R G G T W K L L G S A
Chicken Gallus gallus XP_001233489 841 93324 R214 R M I R M D R R G G T W K L L
Frog Xenopus laevis P70057 377 42627
Zebra Danio Brachydanio rerio XP_697081 974 106699 R233 R M V R M D R R G G T W K L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 90.1 N.A. N.A. 95.4 95.1 N.A. 76.9 49.6 22.3 37.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 90.6 N.A. N.A. 97.1 97 N.A. 83.2 62.5 30.9 53.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 100 20 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 100 20 0 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 23 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 67 67 0 23 23 0 0 67 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 67 0 0 23 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 67 67 0 23 23 % L
% Met: 0 89 0 0 23 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 89 0 0 89 67 0 23 23 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 23 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 67 0 0 23 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _